Dosis dan Saran Penggunaan:
1x sehari 2 kapsul.
Manfaat:
Membantu memelihara kesehatan saluran kemih
Keunikan, Mekanisme Kerja & Farmakologi:
- Berbahan dasar alami 100% dari ekstrak murni buah cranberry atau vaccinum macrocarpan fructus yang diproses dengan standar farmasi.
- Bekerja dengan cara menangkap bakteri E. Coli sehingga bakteri tersebut tidak dapat menempel di saluran kemih.
- Tidak menyebabkan ketergantungan dan resistensi.
Komposisi:
Vaccinium macrocarpon fructus 250 mg.
Kemasan:
Boks, 5 strip @6 kapsul.
Referensi Ilmiah
[1] Shirby A. Ch Sumolang, John Porotu’o, Standy Soeliongan. Pola Bakteri Penderita Infeksi Saluran Kemih di BLU RSUP Prof. Dr. R. D. Kandou Manado. Fakultas Kedokteran Universitas Ratulangi.
[2] Ales Vidlar, Jitka Vostalova, et al. The Effectiveness of Dried Cranberries (Vaccinium macrocarpon) in Men With Lower Urinary Tract Symptomps. Britsh Journal Nutrition. 2010; 104:1181-1189.
[3] Henky Mohammad Masteryanto. Infeksi Saluran Kemih Sebagai Faktor Risiki Terjadinya Persalinan Preterm. 2015; 23:75-81.
[4] Kaviya Srinidhi. Cranberry and Its Actibacterial Activity- A Review. 2014; 6(1);41-44.
[5] Darren M. Lynch. Cranberry for Preservation of Urinary Tract Infections. American Family Physician. 2004; 70(11);2175-2177.
[6] Dugoua JJ et al.Safety and efficacy of cranberry (vaccinium macrocarpon) during pregnancy and lactation. Can J Clin Pharmacol. 2008 Winter;15(1):e80-6. Epub 2008 Jan 18.
[7] Déziel B et al. American cranberry (Vaccinium macrocarpon) extract affects human prostate cancer cell growth via cell cycle arrest by modulating expression of cell cycle regulators. Food Funct. 2012 May;3(5):556-64. doi: 10.1039/c2fo10145a. Epub 2012 Mar 5.
[8] Murphy BT, MacKinnon SL, Yan X, Hammond GB, Vaisberg AJ, Neto CC. Identification of triterpene hydroxycinnamates with in vitro antitumor activity from whole cranberry fruit (Vaccinium macrocarpon). J Agric Food Chem. 2003;51:3541-5. doi: 10.1021/jf034114g.
[9] Kondo M, MacKinnon SL, Craft CC, Matchett MD, Hurta RA, Neto CC. Ursolic acid and its esters: occurnece in cranberries and other Vaccinium fruit and effects on matrix metalloproteinase activity in DU145 prostate tumor cells. J Sci Food Agric. 2011;91:789-96. doi: 10.1002/jsfa.4330.
[10] Ahmed Al-Badr et al. Recurrent Urinary Tract Infections Management in Women A review. Sultan Qaboos Univ Med J. 2013 Aug; 13(3): 359–367. Published online 2013 Jun 25.
[11] https://www.mayoclinic.org/diseases-conditions/urinary-tract-infection/symptoms-causes/syc-20353447 diakses pada 29 Januari 2020.
[12] Chee Wei Tan, Maciej Piotr Chlebicki. Urinary Tract Infections in Adults. Singapore Medical Journal. 2016; 57(9): 485-490.
[13] John M. Rosen, David J Klumpp. Mechanisms Of Pain From Urinary Tract Infection. International Journal Urology. 2014; 21(0 1): 26–32.
[14] Marcelo Hisano,I Homero Bruschini, et al. Cranberries And Lower Urinary Tract Infection Prevention. CLINICS. 2012;67(6):661-667.
[15] Katherine M. Weh, Jennifer Clarke, and Laura A. Kresty. Cranberries and Cancer: An Update of Preclinical Studies Evaluating the Cancer Inhibitory Potential of Cranberry and Cranberry Derived Constituents. Antioxidants. 2016, 5(27).
[16] Manabe, E. et al. Astaxanthin Protects Mesangial Cells From Hyperglycemia-Induced Oxidative Signaling. Journal Cell Biochem. (2008) 103(6):1925-37.
